Relating membrane potential to impedance spectroscopy

Relating membrane potential to impedance spectroscopy

Non-invasive, label-free assessment of membrane potential of living cells is still a challenging task. The theory linking membrane potential to the low frequency α dispersion exhibited by suspensions of spherical shelled particles (presenting a net charge distribution on the inner side of the shell) has been pioneered in our previous studies with emphasis on the permittivity spectra. Whereas α ...

Mitochondrial Membrane Studies Using Impedance Spectroscopy with Parallel pH Monitoring

A biological microelectromechanical system (BioMEMS) device was designed to study complementary mitochondrial parameters important in mitochondrial dysfunction studies. Mitochondrial dysfunction has been linked to many diseases, including diabetes, obesity, heart failure and aging, as these organelles play a critical role in energy generation, cell signaling and apoptosis. The synthesis of ATP ...

An integrated approach to electrochemical impedance spectroscopy

A philosophy for electrochemical impedance spectroscopy is presented which integrates experimental observation, model development, and error analysis. This approach is differentiated from the usual sequential model development for given impedance spectra by its emphasis on obtaining supporting observations to guide model selection, use of error analysis to guide regression strategies and experi...

Impedance Spectroscopy of Thin Films

Single Crystal by Impedance Spectroscopy

Bi 4 Ge 3 O 12 (bismuth germanate – BGO) single crystals were produced by the Czochralski technique and their electrical and dielectric properties were investigated by impedance spectroscopy. The isothermal ac measurements were performed for temperatures from room temperature up to 750 °C, but only the data taken above 500 °C presented a complete semicircle in the complex impedance diagrams. Ex...